LITTLE KNOWN FACTS ABOUT PKRRATING.

The activated enzyme then phosphorylates its key substrate, the translational initiation component eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs to a conserved spouse and children of four protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in reaction to unique stimuli12, triggering the integr